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Simone Oech

Simone Oech 

Tugging on the tail of something bigger, trying to be true and practicing joy

Beschäftigung: I have opinions. I am willing to share.

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Views: 205,717

Auf CircleCount.com aufgenommen: 01/08/2012That's the date, where Simone Oech has been indexed by CircleCount.com.
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Die Top Beiträge aus den letzten 50 Beiträgen

Die meisten Kommentare: 5

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2016-05-09 13:19:33 (5 comments; 0 reshares; 7 +1s)Open 


Cruelty-free mousetrap

Die meisten Reshares: 2

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2016-05-25 09:18:54 (0 comments; 2 reshares; 9 +1s)Open 

Die meisten +1: 11

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2016-04-26 18:02:46 (0 comments; 0 reshares; 11 +1s)Open 

Sadness indeed. 

Die Letzten 50 Beiträge

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2016-05-25 18:41:47 (0 comments; 1 reshares; 0 +1s)Open 

Waaaaaaaaaaaaaaaaant!

This wood burning camp stove combines the benefits of a lightweight backpacking stove and an off-grid power charger.

http://technology.ideas2live4.com/2016/05/13/wood-burning-camp-stove-that-charges-your-electronics/

You can cook a meal while converting excess heat from the fire into usable electricity that can charge your electronics.

Could you use one on your next camping trip?___Waaaaaaaaaaaaaaaaant!

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2016-05-25 12:25:17 (0 comments; 0 reshares; 1 +1s)Open 

So.... ignorance can be deliberately spread.
Definition of ignorance: lack of knowledge, information, or education; the state of being ignorant. Word Origin and History for ignorance Expand. n. c.1200, from Old French ignorance (12c.), from Latin ignorantia "want of knowledge" (see ignorant).

Definition of stupidity: Stupidity is a lack of intelligence, understanding, reason, wit or sense. Stupidity may be innate, assumed or reactive – a defence against grief or trauma.

I would rather be called ignorant- because I can gain knowledge and change that state.

If you haven't read this article about propaganda intended to instill doubt and ignorance, it's worth your time.___So.... ignorance can be deliberately spread.
Definition of ignorance: lack of knowledge, information, or education; the state of being ignorant. Word Origin and History for ignorance Expand. n. c.1200, from Old French ignorance (12c.), from Latin ignorantia "want of knowledge" (see ignorant).

Definition of stupidity: Stupidity is a lack of intelligence, understanding, reason, wit or sense. Stupidity may be innate, assumed or reactive – a defence against grief or trauma.

I would rather be called ignorant- because I can gain knowledge and change that state.

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2016-05-25 10:47:01 (0 comments; 1 reshares; 3 +1s)Open 

Anyone for applying themselves and staying more anonymous?

Because "I have nothing to hide" really isn't the same as "everything I do should be broadcast publicly."

I've had this post in mind for some time as I've seen more and more deeply personal data spread across the web. Ashley Madison is a perfect example of that and many people were shocked at just how many real identities were contained in the data, identities that then caused a great deal of grief for their owners.
...
Online privacy is not necessarily about having something to hide, it's often about simply not wanting to share certain activities. If you consider that everything you do on the web might one day become public, you may well find there are classes of site you use where privacy is actually rather important.___Anyone for applying themselves and staying more anonymous?

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2016-05-25 09:18:54 (0 comments; 2 reshares; 9 +1s)Open 

Very, very important info.
Relevant extract here:
Drowning is almost always a deceptively quiet event. The waving, splashing, and yelling that dramatic conditioning (television) prepares us to look for is rarely seen in real life.
The Instinctive Drowning Response—so named by Francesco A. Pia, Ph.D., is what people do to avoid actual or perceived suffocation in the water. And it does not look like most people expect. There is very little splashing, no waving, and no yelling or calls for help of any kind. To get an idea of just how quiet and undramatic from the surface drowning can be, consider this: It is the No. 2 cause of accidental death in children, ages 15 and under (just behind vehicle accidents)—of the approximately 750 children who will drown next year, about 375 of them will do so within 25 yards of a parent or other adult. According to the CDC, in 10 percent of those drownings,the... mehr »

___Very, very important info.
Relevant extract here:
Drowning is almost always a deceptively quiet event. The waving, splashing, and yelling that dramatic conditioning (television) prepares us to look for is rarely seen in real life.
The Instinctive Drowning Response—so named by Francesco A. Pia, Ph.D., is what people do to avoid actual or perceived suffocation in the water. And it does not look like most people expect. There is very little splashing, no waving, and no yelling or calls for help of any kind. To get an idea of just how quiet and undramatic from the surface drowning can be, consider this: It is the No. 2 cause of accidental death in children, ages 15 and under (just behind vehicle accidents)—of the approximately 750 children who will drown next year, about 375 of them will do so within 25 yards of a parent or other adult. According to the CDC, in 10 percent of those drownings, the adult will actually watch the child do it, having no idea it is happening. Drowning does not look like drowning—Dr. Pia, in an article in the Coast Guard’s On Scene magazine, described the Instinctive Drowning Response like this:
“Except in rare circumstances, drowning people are physiologically unable to call out for help. The respiratory system was designed for breathing. Speech is the secondary or overlaid function. Breathing must be fulfilled before speech occurs.
Drowning people’s mouths alternately sink below and reappear above the surface of the water. The mouths of drowning people are not above the surface of the water long enough for them to exhale, inhale, and call out for help. When the drowning people’s mouths are above the surface, they exhale and inhale quickly as their mouths start to sink below the surface of the water.
Drowning people cannot wave for help. Nature instinctively forces them to extend their arms laterally and press down on the water’s surface. Pressing down on the surface of the water permits drowning people to leverage their bodies so they can lift their mouths out of the water to breathe.
Throughout the Instinctive Drowning Response, drowning people cannot voluntarily control their arm movements. Physiologically, drowning people who are struggling on the surface of the water cannot stop drowning and perform voluntary movements such as waving for help, moving toward a rescuer, or reaching out for a piece of rescue equipment.
From beginning to end of the Instinctive Drowning Response people’s bodies remain upright in the water, with no evidence of a supporting kick. Unless rescued by a trained lifeguard, these drowning people can only struggle on the surface of the water from 20 to 60 seconds before submersion occurs.”
This doesn’t mean that a person that is yelling for help and thrashing isn’t in real trouble—they are experiencing aquatic distress. Not always present before the Instinctive Drowning Response, aquatic distress doesn’t last long—but unlike true drowning, these victims can still assist in their own rescue. They can grab lifelines, throw rings, etc.
Look for these other signs of drowning when persons are in the water:
- Head low in the water, mouth at water level
- Head tilted back with mouth open
- Eyes glassy and empty, unable to focus
- Eyes closed
- Hair over forehead or eyes
- Not using legs—vertical
- Hyperventilating or gasping
- Trying to swim in a particular direction but not making headway
- Trying to roll over on the back
- Appear to be climbing an invisible ladder
So if a crew member falls overboard and everything looks OK—don’t be too sure. Sometimes the most common indication that someone is drowning is that they don’t look like they’re drowning. They may just look like they are treading water and looking up at the deck. One way to be sure? Ask them, “Are you all right?” If they can answer at all—they probably are. If they return a blank stare, you may have less than 30 seconds to get to them. And parents—children playing in the water make noise. When they get quiet, you get to them and find out why._

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2016-05-25 09:09:26 (0 comments; 0 reshares; 3 +1s)Open 

I have always thought/ experienced that music changes "things" (emotions, mood) when I listen. That is why I have a group of playlists that I use at different times.
So this makes good sense to me.... and it is about time to remember that a human ia a sensing being, and that all the senses are activated and involved in experiences. We just don't always pay attention.
And "drugs" tend to remove filters- or change them.


What One Scientist Has Learned From Selecting The Music That People Listen To On LSD, During Clinical Trials


Mendel Kaelen, a PhD student in neuroscience at Imperial College, has led several studies investigating the combined influence of music and psychedelic drugs in human trials.

One of the challenges? Choosing the music.

In recent trials, it’s been Kaelen’s responsibility (among other things) to design the perfect playlist for a scientifically-sanctioned psychedelic trip with strict research requirements, a task that requires both a creative sensibility and a respect for the rigorous framework of scientific procedures.


He explained that the need to include music in these trials is borne directly from the rising interest in studying psychedelic drugs and considering how they could be used therapeutically:

One of the main purposes of the Imperial College team’s research with these substances is to explore how they might be used to help treat mental illnesses such as depression.

...


What music is suitable for judging emotional responses on acid?

The participants listened to two different playlists, the “emotional potency” of which were balanced based on earlier assessments from a separate group of people.

The selected tracks were among those judged most likeable and least familiar—Kaelen explained that familiarity with a track could influence people’s emotional response.

“If music is too familiar, it can reduce the ability to have a new experience, because you already had an experience with that song before in your life,” he noted.

The resulting playlists both include ambient and neo-classical tracks by artists Brian McBride, Ólafur Arnalds, Arve Henriksen, and Greg Haines. Kaelen said Haines, a British composer, was a popular choice—he’s used tracks by him in several trials.

“His song was just pointed out again and again as a favourite, so to speak,” he said.

The participants in the emotional response study were asked to rate how emotionally affected they were by the music on a scale of 1-100 and to complete a questionnaire known as the GEMS-9, which asked them to give a rating for different kinds of emotional responses to the music, such as peacefulness or tension.

The researchers found that participants reported a significantly higher emotional response to the music when they took LSD, and that emotions related to “wonder,” “transcendence,” “tenderness,” and “power” were particularly increased.

...


The study, published in European Neuropsychopharmacology, found that information flow between the parahippocampal cortex—which has been linked to memory—and the visual cortex was reduced under LSD.

But with music as well, communication between these two areas increased.

Importantly, the magnitude of this effect correlated with people reporting more complex visions and particularly images that were autobiographical in nature.

“Very often, people have vivid, eyes-closed imagery, where they are interacting—it’s not like they’re looking at a screen where they see certain images that are entertaining; there’s a personal interaction with that imagery,” said Kaelen.

The personal nature of the psychedelic experience makes it tough to pick a soundtrack.

“That was a very challenging thing actually, because we all have different musical preferences of course,” said Kaelen. They couldn’t allow people to bring their own music as they needed to standardize practices in order to get clean scientific data.

Kaelen started by selecting a library of music which was then put to a separate group to be rated on their emotional impact.

“Initially I wanted to work with very evocative, very emotionally strong neo-classical music, but considering the challenging environment people are in within the fMRI scanner, I actually thought maybe it wouldn’t be a good idea to expose people to really intense emotional environment,” he explained.

“I ended up selecting music that has a very relaxing and very positive general atmosphere within it—mainly music by an ambient music artist called Robert Rich.”

{Ucch... I am not an ambient music fan... If it's not an acoustic or unplugged, non-computerized, non-pretend instrument and/or a real voice, I don't want to hear it...  ~RA }

...

While these studies have shed light on the effects of music and LSD when experienced in combination, a driving force of the Imperial College team’s research is to explore how psychedelics could be used in a therapeutic context.

Research has shown that, used under the guidance of a therapist, these drugs could be useful in treating illnesses such as depression, anxiety, and addiction. Kaelen is interested in how music can help.

The basic idea has its roots in psychedelic therapy in the 60s, before these drugs became illegal and therefore harder to work with.

“People started to realize that it’s not the drug itself that provides a therapeutic effect; it’s the experience that the drug is able to produce in interaction with the therapist, with the environment, that has that potential,” explained Kaelen.

“Out of this realization, people basically started to experiment with different ways of how to design the experience; how to make sure that people have an experience that is indeed therapeutic.”

Music was soon recognized as a way to try to help provide some structure to the experience.

Recently, Kaelen was involved in a clinical trial that involved giving psilocybin—the psychedelic compound in “magic mushrooms”—to patients with treatment-resistant depression. (The results have not yet been published.)

The trial took place in a hospital room decorated to look less clinical and scary—Kaelen noted that the sterile hospital room was probably “one of the worst places to take a psychedelic drug.”

...

Putting together a playlist for this trial was much more challenging, as it needed to soundtrack the therapeutic environment for around six hours, as opposed to the few minutes in the brain imaging study.

Patients could either listen through the sound system in the room or through earbuds, but the music was always on.

Kaelen said his playlist was partly inspired by the work of previous researchers such as music therapist Helen Bonny, who developed a method called Guided Imagery and Music in the 60s to help explore states of consciousness in a therapeutic context.

He designed his playlist to reflect the changing experience of the drug, from the onset of the psilocybin effects building up to the peak of the experience and then the comedown. “For all these different phases within the playlist, different needs are there to be met that the music can help with,” said Kaelen.

For example, many people are naturally nervous before the drug takes effect, so Kaelen selected music that might be calming and reassuring.

During the onset, the music becomes more rhythmic, and during the peak of the drug’s effect, which lasts a couple of hours, the music swings between different emotional intensities in what Kaelen called a pendulum effect.

...

To demonstrate the effect of the music, Kaelen shared with me some patient experiences. In response to “183 Times,” one patient said it was “The peak of the experience, the track that seemed to sum up the whole experience. Moved beyond words, it accompanied the strongest part of the inner journey. Mind blowing."
...

There’s not really a science to it—at least not yet.

“To be honest with you, when I started doing it, I also felt the huge responsibility that designing a music playlist like this brings, because people will be influenced by it incredibly,” he admitted.

One major thing Kaelen took from the trial was that, while he still believes there is some universality to music, it’s impossible to make a standardized playlist suitable for everyone.

He suggests that in the future, a therapist should have some way of adapting the music to their individual patients’ needs. Moving forward, that’s something he’s working on.

He emphasized that the most important aspect of using psychedelics therapeutically was having a strong rapport between patient and therapist.

“The music is, in essence, always and only there to be in service of the central therapeutic process; that is to support the highly personal eyes-closed journey that is unfolding over the hours,” he said.


text omitted...___I have always thought/ experienced that music changes "things" (emotions, mood) when I listen. That is why I have a group of playlists that I use at different times.
So this makes good sense to me.... and it is about time to remember that a human ia a sensing being, and that all the senses are activated and involved in experiences. We just don't always pay attention.
And "drugs" tend to remove filters- or change them.

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2016-05-25 06:45:42 (0 comments; 0 reshares; 1 +1s)Open 

Ok, step has... evolved. All I can say is.. wow. And - enjoy!


t/h +Tejas Richard 

Like I said to the person that shared it with me: I never knew this was something I needed to see before now. I'm unable to stop watching since I've seen it.___Ok, step has... evolved. All I can say is.. wow. And - enjoy!


t/h +Tejas Richard 

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2016-05-23 06:30:39 (0 comments; 0 reshares; 1 +1s)Open 

I feel fortunate to be able to speak two languages.
And a little stupid because it is only two. Many around me (in Europe) speak 3-4 languages.

Poor Rosemarie, afraid of the world around her. Pauvre Rosemarie, a peur du monde autour d'elle. Arme Rosemarie, ze is bang voor de wereld om haar heen. गरीब Rosemarie, वह अपने आसपास की दुनिया से डर लगता है। แย่ Rosemarie เธอกลัวของโลกรอบตัวเธอ
___I feel fortunate to be able to speak two languages.
And a little stupid because it is only two. Many around me (in Europe) speak 3-4 languages.

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2016-05-23 05:56:25 (1 comments; 0 reshares; 5 +1s)Open 

Corporation : "No, no, it is 'reprocessed water' "


t/h +Scott Cramer 

via +Chase Barnes ___Corporation : "No, no, it is 'reprocessed water' "


t/h +Scott Cramer 

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2016-05-19 13:25:17 (1 comments; 0 reshares; 2 +1s)Open 

Someone posted something to the Addams family film. Which reminded me of this. I do like Wednesday!
There are several seasons of several episodes each. I was thrilled.

Someone posted something to the Addams family film. Which reminded me of this. I do like Wednesday!
There are several seasons of several episodes each. I was thrilled.___

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2016-05-19 12:43:59 (1 comments; 1 reshares; 3 +1s)Open 

On the one hand, i could not stop giggling. On the other hand.... its sad.

___On the one hand, i could not stop giggling. On the other hand.... its sad.

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2016-05-19 12:10:47 (0 comments; 0 reshares; 2 +1s)Open 

Yes, yes, yes, YES! Sixpack rings harm, deform and kill so many lifeforms. Never another plastic sixpack thingy!!!!!


t/h +AdmiralLadyPaula Rizzuto 

"They are 100% biodegradable and edible and are created from the barley and wheat ribbons from the brewing process."

Nice!___Yes, yes, yes, YES! Sixpack rings harm, deform and kill so many lifeforms. Never another plastic sixpack thingy!!!!!


t/h +AdmiralLadyPaula Rizzuto 

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2016-05-19 10:59:49 (0 comments; 1 reshares; 5 +1s)Open 

That is the kind of place I would want to go if one day I had to. I visit in a "senior home" once a week over the last months. I find it.... horrifying. Even tho this particular one isconsidered a "good one".

For More Join ► +DID YOU KNOW ?​___That is the kind of place I would want to go if one day I had to. I visit in a "senior home" once a week over the last months. I find it.... horrifying. Even tho this particular one isconsidered a "good one".

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2016-05-18 18:53:52 (2 comments; 0 reshares; 4 +1s)Open 

Someone who is open to thinking, learning and questioning. And he has put together a great summary of what he has learned.
I am not baptist... I don't really care what is background is. I care that he questions, thinks an learns.

___Someone who is open to thinking, learning and questioning. And he has put together a great summary of what he has learned.
I am not baptist... I don't really care what is background is. I care that he questions, thinks an learns.

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2016-05-18 18:11:28 (1 comments; 0 reshares; 4 +1s)Open 

Loved the film, series was part of my childhood. And for a while, there was an actress doing shorts of "Wednesday" grown up. unfortunately, sadly, the "owners" of the Adams Family forced her to stop. At least, that is my information at the moment. Stupid of them......

No WONDER I loved that show as a kid!___Loved the film, series was part of my childhood. And for a while, there was an actress doing shorts of "Wednesday" grown up. unfortunately, sadly, the "owners" of the Adams Family forced her to stop. At least, that is my information at the moment. Stupid of them......

2016-05-18 11:47:18 (2 comments; 0 reshares; 2 +1s)Open 

Bang on!

___Bang on!

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2016-05-17 08:15:52 (0 comments; 0 reshares; 0 +1s)Open 

I love this site, and anyon who has time and delight in well formed words, and wants to learn about fascinating books... GO HERE!
This particular article brought me to tears, and I will buy the book described, because I will want to read it again, and also give it to others to read. It may be written for children, but all of us have a child within us.

I love this site, and anyon who has time and delight in well formed words, and wants to learn about fascinating books... GO HERE!
This particular article brought me to tears, and I will buy the book described, because I will want to read it again, and also give it to others to read. It may be written for children, but all of us have a child within us.___

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2016-05-17 07:54:21 (0 comments; 0 reshares; 3 +1s)Open 

Well done! Never underestimate!
Technology is vunerable.

A Russian Man Armed With a Spear Takes Down Flying Drone at a History Festival in Russia___Well done! Never underestimate!
Technology is vunerable.

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2016-05-17 07:45:02 (0 comments; 0 reshares; 2 +1s)Open 

Further insanity perpetrated by polititians in the US of A .... land of the (not)Free


#waronwomen

t/h +Mudhooks 

___Further insanity perpetrated by polititians in the US of A .... land of the (not)Free


#waronwomen

t/h +Mudhooks 

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2016-05-15 08:25:58 (0 comments; 1 reshares; 0 +1s)Open 

What a neat idea! And I find Ms. Atwood's work compelling. And the Handmaids Tale is eerily close to what I find certain factions want to see as real in the States.

I just happened upon this tidbit and I find it enchanting. Oh how I devoured Ms. Atwood's work, especially "Surfacing."___What a neat idea! And I find Ms. Atwood's work compelling. And the Handmaids Tale is eerily close to what I find certain factions want to see as real in the States.

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2016-05-14 15:29:37 (3 comments; 1 reshares; 7 +1s)Open 

All very good ideas. I do some of them..... I think with a bit of care I can do more.
And you?

___All very good ideas. I do some of them..... I think with a bit of care I can do more.
And you?

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2016-05-14 07:10:16 (0 comments; 0 reshares; 1 +1s)Open 

Alle wissen "eigentlich" das es sch**ße ist, und das die Armen Teilnehmer nicht so recht wissen was mit ihnen geschiet.
Und jetzt: belegt. Also, hört auf euch aufzugeilen and so einer Sendung. Wo keine nachfrage ist, .........

Nice.___Alle wissen "eigentlich" das es sch**ße ist, und das die Armen Teilnehmer nicht so recht wissen was mit ihnen geschiet.
Und jetzt: belegt. Also, hört auf euch aufzugeilen and so einer Sendung. Wo keine nachfrage ist, .........

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2016-05-13 22:10:50 (0 comments; 0 reshares; 5 +1s)Open 

I so really enjoy going grey. I feel... more myself.

I so really enjoy going grey. I feel... more myself.___

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2016-05-12 12:19:21 (0 comments; 0 reshares; 6 +1s)Open 

This is .... utterly awesome.
The breadth of his vision, and the feasability of it. I am reposting so hopefully someone will catch fire and join him (and the other sea farmers)!!


t/h +Uche Eke 

More information can be found here: http://greenwave.org/

1. http://www.theguardian.com/sustainable-business/2015/oct/22/greenwave-ocean-farming-bren-smith-fuller-challenge-sustainability-climate-change

___This is .... utterly awesome.
The breadth of his vision, and the feasability of it. I am reposting so hopefully someone will catch fire and join him (and the other sea farmers)!!


t/h +Uche Eke 

More information can be found here: http://greenwave.org/

1. http://www.theguardian.com/sustainable-business/2015/oct/22/greenwave-ocean-farming-bren-smith-fuller-challenge-sustainability-climate-change

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2016-05-12 11:55:05 (1 comments; 0 reshares; 3 +1s)Open 

Visuwords- very cool!! A visual Thesarus, basically, but with even more info.
+Bruce Shark : it might be hard to see, but that is the result for "shark"



t/h +Literally Literary & +miri dunn 

Visuwords- very cool!! A visual Thesarus, basically, but with even more info.
+Bruce Shark : it might be hard to see, but that is the result for "shark"



t/h +Literally Literary & +miri dunn ___

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2016-05-11 08:04:40 (0 comments; 0 reshares; 0 +1s)Open 

Und was ich erschreckend finde, genau das könnte in Deutschland passieren. Wie in diesem Artikel geschrieben, befürchte ich das dass selbe hier passiert:
Aus Angst vor Rassismus-Vorwürfen ignorierten britische Sozialarbeiter jahrelang Missbrauchsfälle. Jetzt beginnt in Großbritannien die große Abrechnung.

Und was ich erschreckend finde, genau das könnte in Deutschland passieren. Wie in diesem Artikel geschrieben, befürchte ich das dass selbe hier passiert:
Aus Angst vor Rassismus-Vorwürfen ignorierten britische Sozialarbeiter jahrelang Missbrauchsfälle. Jetzt beginnt in Großbritannien die große Abrechnung.___

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2016-05-11 06:33:16 (0 comments; 0 reshares; 1 +1s)Open 

Wenn auch nur eine weitere Person dieses interview hört, dann hat es sich gelohnt es hier zu "posten".
Es ist knapp mehr als 15 Minuten.

Sie ist toll, er ist eine Pappnase, scheint mir nichts zu verstehen.


h/t +Ines Klein 

___Wenn auch nur eine weitere Person dieses interview hört, dann hat es sich gelohnt es hier zu "posten".
Es ist knapp mehr als 15 Minuten.

Sie ist toll, er ist eine Pappnase, scheint mir nichts zu verstehen.


h/t +Ines Klein 

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2016-05-10 22:45:27 (2 comments; 0 reshares; 6 +1s)Open 

Big words. Every sentence.
Words. Much sense, too. Oh! A comma! With words.

t/h +Colin Fish 

___Big words. Every sentence.
Words. Much sense, too. Oh! A comma! With words.

t/h +Colin Fish 

2016-05-10 11:00:01 (0 comments; 0 reshares; 0 +1s)Open 

This is a neat site to add a bit of "something" to your posts. 🎩

🌾🌾🌾🌾🌾🌾🌾🌾🌾🌾🌾🌾🌾🌾🌾🌾🌾🌾🌾🌾🌾🌾🌾🌾🌾🌾🌾

This is a neat site to add a bit of "something" to your posts. 🎩

🌾🌾🌾🌾🌾🌾🌾🌾🌾🌾🌾🌾🌾🌾🌾🌾🌾🌾🌾🌾🌾🌾🌾🌾🌾🌾🌾___

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2016-05-10 10:52:53 (1 comments; 0 reshares; 4 +1s)Open 

This one's for you
+Bruce Shark 😊 🐬🐬🐬

This one's for you
+Bruce Shark 😊 🐬🐬🐬___

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2016-05-09 13:47:04 (0 comments; 0 reshares; 0 +1s)Open 

Want to do your own bit of research?

t/h +Kerry Amburgy-Dickson 

One of the biggest databases of leaked documents has just hit the Internet.___Want to do your own bit of research?

t/h +Kerry Amburgy-Dickson 

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2016-05-09 13:19:33 (5 comments; 0 reshares; 7 +1s)Open 

DIY live mousetrap.
Simple and elegant!


Cruelty-free mousetrap___DIY live mousetrap.
Simple and elegant!

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2016-05-04 06:43:48 (0 comments; 0 reshares; 4 +1s)Open 

I am deeply glad that Ted Cruz has given up .... for now. He is even scarier than Trump, because of his aim to marry the government to the Christian Church.
That does not mean that Trump doesn't give me the heebie-jeebies too.

I am deeply glad that Ted Cruz has given up .... for now. He is even scarier than Trump, because of his aim to marry the government to the Christian Church.
That does not mean that Trump doesn't give me the heebie-jeebies too.___

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2016-05-04 06:04:57 (0 comments; 0 reshares; 0 +1s)Open 

I am chewing on this. I think this is very important....... and that it has been forgotten in large part. So, here is my bit- posted for me to remember, and perhaps it will mean something to others.

And I will be exercising my self respect muscle.
And the site has alot more riches than just this article.

I am chewing on this. I think this is very important....... and that it has been forgotten in large part. So, here is my bit- posted for me to remember, and perhaps it will mean something to others.

And I will be exercising my self respect muscle.
And the site has alot more riches than just this article.___

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2016-05-04 05:53:58 (0 comments; 0 reshares; 0 +1s)Open 

And a narcissist at the helm of the US???
From the article:
Trump’s ongoing campaign and success support the notion that narcissistic leaders can be highly successful and organizationally effective. However, recent work provides a stark contrast to this belief based on reports from leaders from a wide range of organizational settings including military, health care and business institutions. The data support a leadership model whose foundation lies in modeling effective behaviors and not grandstanding or “pretending.” Barbora Nevicka et al. provided support against a narcissistic leader showing that “although narcissistic leaders are perceived as effective because of their displays of authority, a leader's narcissism actually inhibits information exchange between group members and thereby negatively affects group performance.” More recently, the inhibition of information exchangehas actually... mehr »

And a narcissist at the helm of the US???
From the article:
Trump’s ongoing campaign and success support the notion that narcissistic leaders can be highly successful and organizationally effective. However, recent work provides a stark contrast to this belief based on reports from leaders from a wide range of organizational settings including military, health care and business institutions. The data support a leadership model whose foundation lies in modeling effective behaviors and not grandstanding or “pretending.” Barbora Nevicka et al. provided support against a narcissistic leader showing that “although narcissistic leaders are perceived as effective because of their displays of authority, a leader's narcissism actually inhibits information exchange between group members and thereby negatively affects group performance.” More recently, the inhibition of information exchange has actually taken the form of sophomoric name-calling, displays of bravado, and the condemnation of entire groups who happen to share the same religious, ethnic or national background.

(link to research papaer about Leaders, Humility and Narcissism:  http://leeds-faculty.colorado.edu/dahe7472/Owens%20and%20Hekman%20Leader%20Humility%202012.pdf )
(link to research on narcissistic leader non-effectivness: http://pss.sagepub.com/content/22/10/1259 )___

2016-04-29 11:12:44 (0 comments; 0 reshares; 0 +1s)Open 

This is good. this is what should be happening.

This is good. this is what should be happening.___

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2016-04-26 18:15:55 (0 comments; 2 reshares; 5 +1s)Open 

Ummmm, no? 
Where is the skin, the smell, the taste? Where is maybe you do, I don't but it doesn't matter because I feel you, or the other way around? 
Oh, the confetti? That is what everyone wants you to believe. It just messes up the ...bedroom.

I've never had an orgasm like that. I can guess where the steam comes from, but what about the confetti?___Ummmm, no? 
Where is the skin, the smell, the taste? Where is maybe you do, I don't but it doesn't matter because I feel you, or the other way around? 
Oh, the confetti? That is what everyone wants you to believe. It just messes up the ...bedroom.

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2016-04-26 18:02:46 (0 comments; 0 reshares; 11 +1s)Open 

Just this......

Sadness indeed. ___Just this......

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2016-04-21 10:23:12 (0 comments; 0 reshares; 1 +1s)Open 

Raising bandwidth

t/h +Icarus Anne Riley 

This one needs a boost, folks, because we’ve been actively helping people, and now the coffers are a bit light. I am on the Board of Directors for the RPG Creators Relief Fund (by way of transparency and bias indication), and I sincerely believe in the…___Raising bandwidth

t/h +Icarus Anne Riley 

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2016-04-20 12:23:07 (0 comments; 0 reshares; 0 +1s)Open 

Vermutlich ist die Vermehrung von Schmeeliedern nicht was Erdoğan sich vorgestellt hat.

Hier auch ein Link zu dem Lied von extra3 : https://www.youtube.com/watch?v=Grdb3zHnizo 

Vermutlich ist die Vermehrung von Schmeeliedern nicht was Erdoğan sich vorgestellt hat.

Hier auch ein Link zu dem Lied von extra3 : https://www.youtube.com/watch?v=Grdb3zHnizo ___

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2016-04-11 16:14:12 (1 comments; 0 reshares; 6 +1s)Open 

Raising Bandwidth!!


Parents With No Formal Training  Made A Medical Breakthrough

I love this story:

Loving parents triumph over adversity, and may have made a discovery that will save their children's lives.

I love these kinds of stories; always.

There are many cases similar to this one, and I think they're not only heartwarming, but they remind us to heed an important lesson, one we all too often ignore.

I know that physicians get frustrated when patients print out reams of material from the internet and bring them in to appointments.

And they have every right to: no professional enjoys being second guessed, and few have time to answer so many questions.

Few patients and clients have the education or the smarts necessary to make proper use of their instincts or desires or explorations, either.

I certainly balked when a customer tried to tell me how to prepare #1 Ahi Tuna: NO, I was not going to serve it 'well done."

And I didn't have time to debate the issue, during service.

So, yeah, I get it.

And doctors are pressed for time. This is mostly due to a broken system, but sure, it's frustrating to have to repeat the same explanations day in and day out, particularly when one knows that they're just indulging someone, and the results will always be the same.

BUT?

Occasionally, humans are intelligent, and they have insights, and they deserve to be listened to.

Even patients, and even restaurant patrons.

I think these stories not only celebrate love and perseverance and speak to the possibilities within us all, but they help us keep our arrogance in check, too.

Good Going, Parents!

Proud of ya', and thank you for not giving up.


~RA

*


Drug may prevent plaque formation and help treat or reverse atherosclerosis, a major cause of heart disease, and the breakthrough was developed by non-medically trained parents who read everything they could, in an effort to save their children

Two parents’ quest to save their twin daughters’ lives from a rare, degenerative genetic disorder may end up saving and improving the lives of millions.

After digging through medical literature and fitting pieces of data together, the non-medically trained couple contacted German researchers and suggested that a chemical called cyclodextrin may be able to treat atherosclerosis—the hardening of arteries with cholesterol-rich plaques, which is a precursor to heart attack, stroke, and other cardiovascular diseases.

The researchers, Eicke Latz at the University of Bonn and colleagues, followed up on the parents’ hypothesis and found that in mice, cyclodextrin indeed blocked plaque formation, melted away plaques that had already formed in arteries, reduced atherosclerosis-associated inflammation, and revved up cholesterol metabolism—even in rodents fed cholesterol-rich diets.

In petri dish-based tests, the researchers found that the drug seemed to have the same effects on human cells and plaques.

The findings, published Wednesday in Science Translational Medicine, suggest that cyclodextrin—a drug already approved for use in humans by the US Food and Drug Administration—may be highly effective at treating and preventing heart disease.

Currently, cardiovascular diseases are the leading cause of death worldwide, and around 43 percent of Americans have high cholesterol, which can lead to atherosclerosis.

Typical treatments include statins and other cholesterol-lowering drugs, which are not always effective, particularly when patients don’t adhere to doctor-prescribed, low-cholesterol diets.

While Latz and co-authors stress that clinical trials are needed to validate the effects of cyclodextrin, the researchers note that it would be fairly easy to repurpose the drug to treat and prevent cardiovascular diseases.

more...



See the paper:

Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming


Dissolving away cholesterol:

Cardiovascular disease resulting from atherosclerosis is one of the most common causes of death worldwide, and additional therapies for this disease are greatly needed because not all patients can be effectively treated with existing approaches. Cyclodextrin is a common FDA-approved substance that is already used as a solubilizing agent to improve delivery of various drugs. Now, Zimmer et al. have discovered that cyclodextrin can also solubilize cholesterol, removing it from plaques, dissolving cholesterol crystals, and successfully treating atherosclerosis in a mouse model. Because cyclodextrin is already known to be safe in humans, this drug is now a potential candidate for testing in human patients for the treatment of atherosclerosis.


Abstract:

Atherosclerosis is an inflammatory disease linked to elevated blood cholesterol concentrations. Despite ongoing advances in the prevention and treatment of atherosclerosis, cardiovascular disease remains the leading cause of death worldwide. Continuous retention of apolipoprotein B–containing lipoproteins in the subendothelial space causes a local overabundance of free cholesterol. Because cholesterol accumulation and deposition of cholesterol crystals (CCs) trigger a complex inflammatory response, we tested the efficacy of the cyclic oligosaccharide 2-hydroxypropyl-β-cyclodextrin (CD), a compound that increases cholesterol solubility in preventing and reversing atherosclerosis. We showed that CD treatment of murine atherosclerosis reduced atherosclerotic plaque size and CC load and promoted plaque regression even with a continued cholesterol-rich diet. Mechanistically, CD increased oxysterol production in both macrophages and human atherosclerotic plaques and promoted liver X receptor (LXR)–mediated transcriptional reprogramming to improve cholesterol efflux and exert anti-inflammatory effects. In vivo, this CD-mediated LXR agonism was required for the antiatherosclerotic and anti-inflammatory effects of CD as well as for augmented reverse cholesterol transport. Because CD treatment in humans is safe and CD beneficially affects key mechanisms of atherogenesis, it may therefore be used clinically to prevent or treat human atherosclerosis.


[http://stm.sciencemag.org/content/8/333/333ra50]





hat tip to +Alessandro Littara , thanks!___Raising Bandwidth!!

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2016-04-07 12:27:20 (2 comments; 1 reshares; 5 +1s)Open 

Its a "goose" and "gander" thing.


t/h +Merritt Awbrey 

___Its a "goose" and "gander" thing.


t/h +Merritt Awbrey 

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2016-04-07 10:43:15 (0 comments; 0 reshares; 2 +1s)Open 

Ok, just for the weird (and funny) of it.

PETTY SONG - The Starrkeisha Cheer Squad

New favorite thing via the never petty always cheers me up starr +Michelle C​!!!

The man has moves. C'mon +Keith Cramer​, let's do it! ;-)___Ok, just for the weird (and funny) of it.

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2016-04-07 10:14:03 (0 comments; 0 reshares; 1 +1s)Open 

What would your cupcake cost?Or, what is it that the conversation is about?

What would your cupcake cost?Or, what is it that the conversation is about?___

2016-04-07 08:20:26 (0 comments; 0 reshares; 1 +1s)Open 

Well, the deadline has passed. I did manage to get my expat vote in. And the delegates were distributed.
But for next time- Democratic Expats can make a difference, and don't have to "disappear" and be subsumed in some states vote.

Well, the deadline has passed. I did manage to get my expat vote in. And the delegates were distributed.
But for next time- Democratic Expats can make a difference, and don't have to "disappear" and be subsumed in some states vote.___

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2016-04-06 12:08:05 (0 comments; 0 reshares; 2 +1s)Open 

Beautiful shop- and the costumes! This is the artist that makes the Butterfly scarves. Partnered with someone who makes steampunk items. What a mix!!!

t/h +Sheila Nagig 

Beautiful shop- and the costumes! This is the artist that makes the Butterfly scarves. Partnered with someone who makes steampunk items. What a mix!!!

t/h +Sheila Nagig ___

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2016-04-04 06:28:24 (0 comments; 0 reshares; 4 +1s)Open 

If you are interested in the back story to the financial scandals that are going to be written about in the next days and weeks, this is it.
For scale: the Swiss leaks were 3,3 GB. The "Offshore" leaks of 2013 were 206 GB. This leak is 2.6 Terabyte.
350 Journalists involved. 1 year of creating and then mining the database for companies, middlemen and connections to the prominent of the world.

___If you are interested in the back story to the financial scandals that are going to be written about in the next days and weeks, this is it.
For scale: the Swiss leaks were 3,3 GB. The "Offshore" leaks of 2013 were 206 GB. This leak is 2.6 Terabyte.
350 Journalists involved. 1 year of creating and then mining the database for companies, middlemen and connections to the prominent of the world.

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